Calcineurin activation contributes to noise-induced hearing loss
نویسندگان
چکیده
منابع مشابه
Calcineurin activation contributes to noise-induced hearing loss.
Acoustic overstimulation increases Ca(2+) concentration in auditory hair cells. Because calcineurin is known to activate cell death pathways and is controlled by Ca(2+) and calmodulin, this study assessed the role of calcineurin in auditory hair cell death in guinea pigs after intense noise exposure. Immediately after noise exposure (4-kHz octave band, 120 dB, for 5 hr), a population of hair ce...
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ژورنال
عنوان ژورنال: Journal of Neuroscience Research
سال: 2004
ISSN: 0360-4012,1097-4547
DOI: 10.1002/jnr.20267